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Association between P16(INK4a) Promoter Methylation and HNSCC: A Meta-Analysis of 21 Published Studies
BACKGROUND: The p16(INK4a) is an important tumor suppressor gene (TSG) and aberrant methylation of promoter is known to be a major inactivation mechanism of the tumor suppressor and tumor-related genes. Aberrant TSG methylation was considered an important epigenetic silencing mechanism in the progre...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383544/ https://www.ncbi.nlm.nih.gov/pubmed/25835498 http://dx.doi.org/10.1371/journal.pone.0122302 |