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Loss of Serum and Glucocorticoid-Regulated Kinase 3 (SGK3) Does Not Affect Proliferation and Survival of Multiple Myeloma Cell Lines

Multiple myeloma (MM) is a generally fatal plasma cell cancer that often shows activation of the phosphoinositide 3-kinase/Akt (PI3K/Akt) pathway. Targeted pharmacologic therapies, however, have not yet progressed beyond the clinical trial stage, and given the complexity of the PI3K/Akt signalling s...

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Detalles Bibliográficos
Autores principales: Hausmann, Stefan, Brandt, Evelyn, Köchel, Carolin, Einsele, Hermann, Bargou, Ralf C., Seggewiss-Bernhardt, Ruth, Stühmer, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383545/
https://www.ncbi.nlm.nih.gov/pubmed/25837824
http://dx.doi.org/10.1371/journal.pone.0122689