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Nxf1 Natural Variant E610G Is a Semi-dominant Suppressor of IAP-Induced RNA Processing Defects

Endogenous retroviruses and retrotransposons contribute functional genetic variation in animal genomes. In mice, Intracisternal A Particles (IAPs) are a frequent source of both new mutations and polymorphism across laboratory strains. Intronic IAPs can induce alternative RNA processing choices, incl...

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Detalles Bibliográficos
Autores principales: Concepcion, Dorothy, Ross, Kevin D., Hutt, Kasey R., Yeo, Gene W., Hamilton, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383553/
https://www.ncbi.nlm.nih.gov/pubmed/25835743
http://dx.doi.org/10.1371/journal.pgen.1005123