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Application of Allogeneic Bone Marrow Cells in View of Residual Alloreactivity: Sirolimus but Not Cyclosporine Evolves Tolerogenic Properties

BACKGROUND: Application of bone marrow cells (BMC) is a promising strategy for tolerance induction, but usually requires strong depletion of the host immune system. This study evaluates the ability of immunosuppressants to evolve tolerogenic properties of BMC in view of residual alloreactivity. METH...

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Detalles Bibliográficos
Autores principales: Timrott, Kai, Vondran, Florian W. R., Bektas, Hueseyin, Klempnauer, Jürgen, Jäger, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383565/
https://www.ncbi.nlm.nih.gov/pubmed/25836261
http://dx.doi.org/10.1371/journal.pone.0119950