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MicroRNA 181b Regulates Decorin Production by Dermal Fibroblasts and May Be a Potential Therapy for Hypertrophic Scar

Hypertrophic scarring is a frequent fibroproliferative complication following deep dermal burns leading to impaired function and lifelong disfigurement. Decorin reduces fibrosis and induces regeneration in many tissues, and is significantly downregulated in hypertrophic scar and normal deep dermal f...

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Detalles Bibliográficos
Autores principales: Kwan, Peter, Ding, Jie, Tredget, Edward E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383602/
https://www.ncbi.nlm.nih.gov/pubmed/25837671
http://dx.doi.org/10.1371/journal.pone.0123054