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Cardiac safety of tiotropium in patients with COPD: a combined analysis of Holter-ECG data from four randomised clinical trials

BACKGROUND: Tiotropium is generally well tolerated; however, there has been debate whether antimuscarinics, particularly tiotropium administered via Respimat® Soft Mist™ Inhaler, may induce cardiac arrhythmias in a vulnerable subpopulation with cardiovascular comorbidity. The aim of this study was t...

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Detalles Bibliográficos
Autores principales: Hohlfeld, J M, Furtwaengler, A, Könen-Bergmann, M, Wallenstein, G, Walter, B, Bateman, E D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383643/
https://www.ncbi.nlm.nih.gov/pubmed/25496316
http://dx.doi.org/10.1111/ijcp.12596