Impaired respiratory function in MELAS-induced pluripotent stem cells with high heteroplasmy levels

Mitochondrial diseases are heterogeneous disorders, caused by mitochondrial dysfunction. Mitochondria are not regulated solely by nuclear genomic DNA but by mitochondrial DNA. It is difficult to develop effective therapies for mitochondrial disease because of the lack of mitochondrial disease models...

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Detalles Bibliográficos
Autores principales: Kodaira, Masaki, Hatakeyama, Hideyuki, Yuasa, Shinsuke, Seki, Tomohisa, Egashira, Toru, Tohyama, Shugo, Kuroda, Yusuke, Tanaka, Atsushi, Okata, Shinichiro, Hashimoto, Hisayuki, Kusumoto, Dai, Kunitomi, Akira, Takei, Makoto, Kashimura, Shin, Suzuki, Tomoyuki, Yozu, Gakuto, Shimojima, Masaya, Motoda, Chikaaki, Hayashiji, Nozomi, Saito, Yuki, Goto, Yu-ichi, Fukuda, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383791/
https://www.ncbi.nlm.nih.gov/pubmed/25853038
http://dx.doi.org/10.1016/j.fob.2015.03.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383791/
https://www.ncbi.nlm.nih.gov/pubmed/25853038
http://dx.doi.org/10.1016/j.fob.2015.03.008

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