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The mechanism of oxythiamine-induced collagen biosynthesis in cultured fibroblasts

The oxythiamine (OXY) is antivitamin of thiamine. The finding that OXY increases the cytoplasmic concentration of pyruvate, known to enhance collagen biosynthesis, led us to investigate the mechanism of this antivitamin action on collagen biosynthesis in cultured human skin fibroblasts. Confluent fi...

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Detalles Bibliográficos
Autores principales: Szoka, Lukasz, Karna, Ewa, Palka, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383821/
https://www.ncbi.nlm.nih.gov/pubmed/25626895
http://dx.doi.org/10.1007/s11010-015-2336-z