Crystal structure of human persulfide dioxygenase: structural basis of ethylmalonic encephalopathy

The ethylmalonic encephalopathy protein 1 (ETHE1) catalyses the oxygen-dependent oxidation of glutathione persulfide (GSSH) to give persulfite and glutathione. Mutations to the hETHE1 gene compromise sulfide metabolism leading to the genetic disease ethylmalonic encephalopathy. hETHE1 is a mono-iron...

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Detalles Bibliográficos
Autores principales: Pettinati, Ilaria, Brem, Jürgen, McDonough, Michael A., Schofield, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383860/
https://www.ncbi.nlm.nih.gov/pubmed/25596185
http://dx.doi.org/10.1093/hmg/ddv007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383860/
https://www.ncbi.nlm.nih.gov/pubmed/25596185
http://dx.doi.org/10.1093/hmg/ddv007

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