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The Candidate Cancer Gene Database: a database of cancer driver genes from forward genetic screens in mice

Identification of cancer driver gene mutations is crucial for advancing cancer therapeutics. Due to the overwhelming number of passenger mutations in the human tumor genome, it is difficult to pinpoint causative driver genes. Using transposon mutagenesis in mice many laboratories have conducted forw...

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Detalles Bibliográficos
Autores principales: Abbott, Kenneth L., Nyre, Erik T., Abrahante, Juan, Ho, Yen-Yi, Isaksson Vogel, Rachel, Starr, Timothy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384000/
https://www.ncbi.nlm.nih.gov/pubmed/25190456
http://dx.doi.org/10.1093/nar/gku770