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TLR-2 Signaling Promotes IL-17A Production in CD4(+)CD25(+)Foxp3(+) Regulatory Cells during Oropharyngeal Candidiasis

Recent studies show that CD4(+)CD25(+)Foxp3(+) regulatory cells (T(regs)) produce effector cytokines under inflammatory conditions. However, the direct role of microbial agents that serve as toll-like receptor (TLR) ligands in the induction of effector cytokines in T(regs) is less clear. Here we sho...

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Detalles Bibliográficos
Autores principales: Bhaskaran, Natarajan, Cohen, Samuel, Zhang, Yifan, Weinberg, Aaron, Pandiyan, Pushpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384074/
https://www.ncbi.nlm.nih.gov/pubmed/25790134
http://dx.doi.org/10.3390/pathogens4010090