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Label-Free Sensing of Adenosine Based on Force Variations Induced by Molecular Recognition

We demonstrate a simple force-based label-free strategy for the highly sensitive sensing of adenosine. An adenosine ssDNA aptamer was bound onto an atomic force microscopy (AFM) probe by covalent modification, and the molecular-interface adsorption force between the aptamer and a flat graphite surfa...

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Detalles Bibliográficos
Autores principales: Li, Jingfeng, Li, Qing, Colombi Ciacchi, Lucio, Wei, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384084/
https://www.ncbi.nlm.nih.gov/pubmed/25808841
http://dx.doi.org/10.3390/bios5010085