Cargando…

Functional xenobiotic metabolism and efflux transporters in trout hepatocyte spheroid cultures

Prediction of xenobiotic fate in fish is important for the regulatory assessment of chemicals under current legislation. Trout hepatocyte spheroids are a promising in vitro model for this assessment. In this investigation, the gene expression and function for xenobiotic metabolism and cellular efflu...

Descripción completa

Detalles Bibliográficos
Autores principales: Uchea, Chibuzor, Owen, Stewart F., Chipman, J. Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384106/
https://www.ncbi.nlm.nih.gov/pubmed/25893091
http://dx.doi.org/10.1039/c4tx00160e