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Molecular Recognition of PTS-1 Cargo Proteins by Pex5p: Implications for Protein Mistargeting in Primary Hyperoxaluria

Peroxisomal biogenesis and function critically depends on the import of cytosolic proteins carrying a PTS1 sequence into this organelle upon interaction with the peroxin Pex5p. Recent structural studies have provided important insights into the molecular recognition of cargo proteins by Pex5p. Perox...

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Detalles Bibliográficos
Autores principales: Mesa-Torres, Noel, Tomic, Nenad, Albert, Armando, Salido, Eduardo, Pey, Angel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384115/
https://www.ncbi.nlm.nih.gov/pubmed/25689234
http://dx.doi.org/10.3390/biom5010121