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Growth Factor Dependent Regulation of Centrosome Function and Genomic Instability by HuR

The mRNA binding protein HuR is over expressed in cancer cells and contributes to disease progression through post-transcriptional regulation of mRNA. The regulation of HuR and how this relates to glioma is the focus of this report. SRC and c-Abl kinases regulate HuR sub-cellular trafficking and inf...

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Detalles Bibliográficos
Autores principales: Filippova, Natalia, Yang, Xiuhua, Nabors, Louis Burt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384122/
https://www.ncbi.nlm.nih.gov/pubmed/25803745
http://dx.doi.org/10.3390/biom5010263