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Mitochondrial respiration and redox coupling in articular chondrocytes

INTRODUCTION: Chondrocytes rely primarily on glycolysis to meet cellular energy needs, but recent studies implicate impaired mitochondrial function in osteoarthritis (OA) pathogenesis. Our objectives were to investigate the ability of chondrocytes to upregulate mitochondrial respiration when challen...

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Detalles Bibliográficos
Autores principales: Lane, Rachel S, Fu, Yao, Matsuzaki, Satoshi, Kinter, Michael, Humphries, Kenneth M, Griffin, Timothy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384316/
https://www.ncbi.nlm.nih.gov/pubmed/25889867
http://dx.doi.org/10.1186/s13075-015-0566-9