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Mitochondrial respiration and redox coupling in articular chondrocytes
INTRODUCTION: Chondrocytes rely primarily on glycolysis to meet cellular energy needs, but recent studies implicate impaired mitochondrial function in osteoarthritis (OA) pathogenesis. Our objectives were to investigate the ability of chondrocytes to upregulate mitochondrial respiration when challen...
Autores principales: | Lane, Rachel S, Fu, Yao, Matsuzaki, Satoshi, Kinter, Michael, Humphries, Kenneth M, Griffin, Timothy M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384316/ https://www.ncbi.nlm.nih.gov/pubmed/25889867 http://dx.doi.org/10.1186/s13075-015-0566-9 |
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