Effect of airway acidosis and alkalosis on airway vascular smooth muscle responsiveness to albuterol

BACKGROUND: In vitro and animal experiments have shown that the transport and signaling of β(2)-adrenergic agonists are pH-sensitive. Inhaled albuterol, a hydrophilic β(2)-adrenergic agonist, is widely used for the treatment of obstructive airway diseases. Acute exacerbations of obstructive airway d...

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Detalles Bibliográficos
Autores principales: Cancado, Jose E, Mendes, Eliana S, Arana, Johana, Horvath, Gabor, Monzon, Maria E, Salathe, Matthias, Wanner, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384333/
https://www.ncbi.nlm.nih.gov/pubmed/25889594
http://dx.doi.org/10.1186/s40360-015-0008-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384333/
https://www.ncbi.nlm.nih.gov/pubmed/25889594
http://dx.doi.org/10.1186/s40360-015-0008-y

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