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Effect of airway acidosis and alkalosis on airway vascular smooth muscle responsiveness to albuterol
BACKGROUND: In vitro and animal experiments have shown that the transport and signaling of β(2)-adrenergic agonists are pH-sensitive. Inhaled albuterol, a hydrophilic β(2)-adrenergic agonist, is widely used for the treatment of obstructive airway diseases. Acute exacerbations of obstructive airway d...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384333/ https://www.ncbi.nlm.nih.gov/pubmed/25889594 http://dx.doi.org/10.1186/s40360-015-0008-y |