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A strategy to build and validate a prognostic biomarker model based on RT-qPCR gene expression and clinical covariates

BACKGROUND: Construction and validation of a prognostic model for survival data in the clinical domain is still an active field of research. Nevertheless there is no consensus on how to develop routine prognostic tests based on a combination of RT-qPCR biomarkers and clinical or demographic variable...

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Detalles Bibliográficos
Autores principales: Tournoud, Maud, Larue, Audrey, Cazalis, Marie-Angelique, Venet, Fabienne, Pachot, Alexandre, Monneret, Guillaume, Lepape, Alain, Veyrieras, Jean-Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384357/
https://www.ncbi.nlm.nih.gov/pubmed/25880752
http://dx.doi.org/10.1186/s12859-015-0537-9