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A strategy to build and validate a prognostic biomarker model based on RT-qPCR gene expression and clinical covariates
BACKGROUND: Construction and validation of a prognostic model for survival data in the clinical domain is still an active field of research. Nevertheless there is no consensus on how to develop routine prognostic tests based on a combination of RT-qPCR biomarkers and clinical or demographic variable...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384357/ https://www.ncbi.nlm.nih.gov/pubmed/25880752 http://dx.doi.org/10.1186/s12859-015-0537-9 |