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Inhibition of interleukin-1beta-stimulated dedifferentiation of chondrocytes via controlled release of CrmA from hyaluronic acid-chitosan microspheres

BACKGROUND: The previous studies indicated that CrmA could ameliorate the interleukin-1β induced osteoarthritis. In this study, we investigated the controlled-released cytokine response modifier A (CrmA) from hyaluronic acid (HA)-chitosan (CS) microspheres to improve interleukin-1β (IL-1β)-stimulate...

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Detalles Bibliográficos
Autores principales: Ma, Bei-lei, Zhou, Pang-Hu, Xie, Ting, Shi, Lei, Qiu, Bo, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384377/
https://www.ncbi.nlm.nih.gov/pubmed/25888442
http://dx.doi.org/10.1186/s12891-015-0521-6