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Alignment-free clustering of transcription factor binding motifs using a genetic-k-medoids approach
BACKGROUND: Familial binding profiles (FBPs) represent the average binding specificity for a group of structurally related DNA-binding proteins. The construction of such profiles allows the classification of novel motifs based on similarity to known families, can help to reduce redundancy in motif d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384390/ https://www.ncbi.nlm.nih.gov/pubmed/25627106 http://dx.doi.org/10.1186/s12859-015-0450-2 |