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Increased Sclerostin Levels after Further Ablation of Remnant Estrogen by Aromatase Inhibitors

BACKGROUND: Sclerostin is a secreted Wnt inhibitor produced almost exclusively by osteocytes, which inhibits bone formation. Aromatase inhibitors (AIs), which reduce the conversion of steroids to estrogen, are used to treat endocrine-responsive breast cancer. As AIs lower estrogen levels, they incre...

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Detalles Bibliográficos
Autores principales: Kim, Wonjin, Chung, Yoonjung, Kim, Se Hwa, Park, Sehee, Bae, Jae Hyun, Kim, Gyuri, Lee, Su Jin, Kim, Jo Eun, Park, Byeong-Woo, Lim, Sung-Kil, Rhee, Yumie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384667/
https://www.ncbi.nlm.nih.gov/pubmed/25827459
http://dx.doi.org/10.3803/EnM.2015.30.1.58