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Increased Sclerostin Levels after Further Ablation of Remnant Estrogen by Aromatase Inhibitors
BACKGROUND: Sclerostin is a secreted Wnt inhibitor produced almost exclusively by osteocytes, which inhibits bone formation. Aromatase inhibitors (AIs), which reduce the conversion of steroids to estrogen, are used to treat endocrine-responsive breast cancer. As AIs lower estrogen levels, they incre...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Endocrine Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384667/ https://www.ncbi.nlm.nih.gov/pubmed/25827459 http://dx.doi.org/10.3803/EnM.2015.30.1.58 |