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Clinical Implication of p16, Ki-67, and Proliferating Cell Nuclear Antigen Expression in Cervical Neoplasia: Improvement of Diagnostic Accuracy for High-grade Squamous Intraepithelial Lesion and Prediction of Resection Margin Involvement on Conization Specimen

BACKGROUND: Cervical intraepithelial neoplasia (CIN) grading is subjective and affected by substantial rates of discordance among pathologists. Although the use of p16INK4a (p16) staining has been proven to improve diagnostic accuracy for high-grade squamous intraepithelial lesion (HSIL), the clinic...

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Detalles Bibliográficos
Autores principales: Kim, Tae Hun, Han, Jee Hye, Shin, Eun, Noh, Jae Hong, Kim, Hee Seung, Song, Yong Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Cancer Prevention 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384717/
https://www.ncbi.nlm.nih.gov/pubmed/25853106
http://dx.doi.org/10.15430/JCP.2015.20.1.70