Cargando…

Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex

Endothelial responses to fluid shear stress are essential for vascular development and physiology, and determine the formation of atherosclerotic plaques at regions of disturbed flow. Previous work identified VE-cadherin as an essential component, along with PECAM-1 and VEGFR2, of a complex that med...

Descripción completa

Detalles Bibliográficos
Autores principales: Coon, Brian G., Baeyens, Nicolas, Han, Jinah, Budatha, Madhusudhan, Ross, Tyler D., Fang, Jennifer S., Yun, Sanguk, Thomas, Jeon-Leon, Schwartz, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384728/
https://www.ncbi.nlm.nih.gov/pubmed/25800053
http://dx.doi.org/10.1083/jcb.201408103