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Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex
Endothelial responses to fluid shear stress are essential for vascular development and physiology, and determine the formation of atherosclerotic plaques at regions of disturbed flow. Previous work identified VE-cadherin as an essential component, along with PECAM-1 and VEGFR2, of a complex that med...
Autores principales: | Coon, Brian G., Baeyens, Nicolas, Han, Jinah, Budatha, Madhusudhan, Ross, Tyler D., Fang, Jennifer S., Yun, Sanguk, Thomas, Jeon-Leon, Schwartz, Martin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384728/ https://www.ncbi.nlm.nih.gov/pubmed/25800053 http://dx.doi.org/10.1083/jcb.201408103 |
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