A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores

Kinetochore (KT) localization of mitotic checkpoint proteins is essential for their function during mitosis. hSpindly KT localization is dependent on the RZZ complex and hSpindly recruits the dynein–dynactin complex to KTs during mitosis, but the mechanism of hSpindly KT recruitment is unknown. Thro...

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Detalles Bibliográficos
Autores principales: Moudgil, Devinderjit K., Westcott, Nathan, Famulski, Jakub K., Patel, Kinjal, Macdonald, Dawn, Hang, Howard, Chan, Gordon K.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384735/
https://www.ncbi.nlm.nih.gov/pubmed/25825516
http://dx.doi.org/10.1083/jcb.201412085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384735/
https://www.ncbi.nlm.nih.gov/pubmed/25825516
http://dx.doi.org/10.1083/jcb.201412085

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