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WISp39 binds phosphorylated Coronin 1B to regulate Arp2/3 localization and Cofilin-dependent motility

We previously identified Waf1 Cip1 stabilizing protein 39 (WISp39) as a binding partner for heat shock protein 90 (Hsp90). We now report that WISp39 has an essential function in the control of directed cell migration, which requires WISp39 interaction with Hsp90. WISp39 knockdown (KD) resulted in th...

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Detalles Bibliográficos
Autores principales: Howell, Michael, Brickner, Howard, Delorme-Walker, Violaine D., Choi, Justin, Saffin, Jean-Michel, Miller, Daniel, Panopoulos, Andreas, DerMardirossian, Céline, Fotedar, Arun, Margolis, Robert L., Fotedar, Rati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384738/
https://www.ncbi.nlm.nih.gov/pubmed/25800056
http://dx.doi.org/10.1083/jcb.201410095