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Role of CD8-positive cells in radioimmunotherapy utilizing (177)Lu-mAbs in an immunocompetent rat colon carcinoma model

BACKGROUND: CD8-positive cells might play a crucial role in the therapeutic response to radiation, which has however not been investigated in radioimmunotherapy (RIT). The aim of this study was to evaluate whether cytotoxic T cells affect the response of established tumors and, above all, if they de...

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Detalles Bibliográficos
Autores principales: Elgström, Erika, Eriksson, Sophie E, Ohlsson, Tomas G, Nilsson, Rune, Tennvall, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385015/
https://www.ncbi.nlm.nih.gov/pubmed/25853009
http://dx.doi.org/10.1186/s13550-014-0079-6