A Mathematical Model of a Midbrain Dopamine Neuron Identifies Two Slow Variables Likely Responsible for Bursts Evoked by SK Channel Antagonists and Terminated by Depolarization Block

Midbrain dopamine neurons exhibit a novel type of bursting that we call “inverted square wave bursting” when exposed to Ca(2+)-activated small conductance (SK) K(+) channel blockers in vitro. This type of bursting has three phases: hyperpolarized silence, spiking, and depolarization block. We find t...

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Detalles Bibliográficos
Autores principales: Yu, Na, Canavier, Carmen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385104/
https://www.ncbi.nlm.nih.gov/pubmed/25852980
http://dx.doi.org/10.1186/s13408-015-0017-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385104/
https://www.ncbi.nlm.nih.gov/pubmed/25852980
http://dx.doi.org/10.1186/s13408-015-0017-6

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