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A Mathematical Model of a Midbrain Dopamine Neuron Identifies Two Slow Variables Likely Responsible for Bursts Evoked by SK Channel Antagonists and Terminated by Depolarization Block
Midbrain dopamine neurons exhibit a novel type of bursting that we call “inverted square wave bursting” when exposed to Ca(2+)-activated small conductance (SK) K(+) channel blockers in vitro. This type of bursting has three phases: hyperpolarized silence, spiking, and depolarization block. We find t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385104/ https://www.ncbi.nlm.nih.gov/pubmed/25852980 http://dx.doi.org/10.1186/s13408-015-0017-6 |