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MELK—a conserved kinase: functions, signaling, cancer, and controversy

Maternal embryonic leucine zipper kinase (MELK) is a highly conserved serine/threonine kinase initially found to be expressed in a wide range of early embryonic cellular stages, and as a result has been implicated in embryogenesis and cell cycle control. Recent evidence has identified a broader spec...

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Detalles Bibliográficos
Autores principales: Ganguly, Ranjit, Mohyeldin, Ahmed, Thiel, Jordyn, Kornblum, Harley I, Beullens, Monique, Nakano, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385133/
https://www.ncbi.nlm.nih.gov/pubmed/25852826
http://dx.doi.org/10.1186/s40169-014-0045-y