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Targeting Human Telomerase Reverse Transcriptase by a Simple siRNA Expression Cassette in HepG2 Cells

BACKGROUND: Human telomerase reverse transcriptase (hTERT) has become an ideal target for development of anticancer therapy. Small interfering RNAs (siRNAs) are very powerful reagents for gene silencing and show promise for cancer gene therapy. However, only a small number of siRNAs have been demons...

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Detalles Bibliográficos
Autores principales: Xu, Hui, Gong, Xia, Zhang, Hui Hui, Zhang, Qin, Zhao, Dandan, Peng, Jian Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kowsar 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385270/
https://www.ncbi.nlm.nih.gov/pubmed/25861317
http://dx.doi.org/10.5812/hepatmon.24343