Cargando…
Targeting Human Telomerase Reverse Transcriptase by a Simple siRNA Expression Cassette in HepG2 Cells
BACKGROUND: Human telomerase reverse transcriptase (hTERT) has become an ideal target for development of anticancer therapy. Small interfering RNAs (siRNAs) are very powerful reagents for gene silencing and show promise for cancer gene therapy. However, only a small number of siRNAs have been demons...
Autores principales: | Xu, Hui, Gong, Xia, Zhang, Hui Hui, Zhang, Qin, Zhao, Dandan, Peng, Jian Xiong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Kowsar
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385270/ https://www.ncbi.nlm.nih.gov/pubmed/25861317 http://dx.doi.org/10.5812/hepatmon.24343 |
Ejemplares similares
-
Multifunctional selenium nanoparticles as carriers of HSP70 siRNA to induce apoptosis of HepG2 cells
por: Li, Yinghua, et al.
Publicado: (2016) -
siRNA directed against c-Myc inhibits proliferation and downregulates human telomerase reverse transcriptase in human colon cancer Colo 320 cells
por: Hao, Huang, et al.
Publicado: (2008) -
Telomerase reverse transcriptase and neurodegenerative diseases
por: Yu, Xin, et al.
Publicado: (2023) -
Deciphering the Functions of Telomerase Reverse Transcriptase in Head and Neck Cancer
por: Yeh, Tsung-Jang, et al.
Publicado: (2023) -
Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase
por: Maida, Yoshiko, et al.
Publicado: (2015)