Protamine nanoparticles for improving shRNA-mediated anti-cancer effects

Protamine nanoparticles were designed by encapsulating small hairpin RNA (shRNA)-expressing plasmid DNA targeting the Bcl-2 gene (shBcl-2) to silence apoptosis-related Bcl-2 protein for improving the transfection efficiency and cytotoxicity in cancer therapy. Our findings demonstrated that the obtai...

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Detalles Bibliográficos
Autores principales: Liu, Ming, Feng, Bo, Shi, Yijie, Su, Chang, Song, Huijuan, Cheng, Wei, Zhao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385308/
https://www.ncbi.nlm.nih.gov/pubmed/25852425
http://dx.doi.org/10.1186/s11671-015-0845-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385308/
https://www.ncbi.nlm.nih.gov/pubmed/25852425
http://dx.doi.org/10.1186/s11671-015-0845-z

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