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Fluorescence-guided development of a tricistronic vector encoding bimodal optical and nuclear genetic reporters for in vivo cellular imaging

BACKGROUND: In vivo imaging using genetic reporters is a central supporting tool in the development of cell and gene therapies affording us the ability to selectively track the therapeutic indefinitely. Previous studies have demonstrated the utility of the human norepinephrine transporter (hNET) as...

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Detalles Bibliográficos
Autores principales: Badar, Adam, Kiru, Louise, Kalber, Tammy L, Jathoul, Amit, Straathof, Karin, Årstad, Erik, Lythgoe, Mark F, Pule, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385325/
https://www.ncbi.nlm.nih.gov/pubmed/25853023
http://dx.doi.org/10.1186/s13550-015-0097-z