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Delay of Morphine Tolerance by Palmitoylethanolamide

In spite of the potency and efficacy of morphine, its clinical application for chronic persistent pain is limited by the development of tolerance to the antinociceptive effect. The cellular and molecular mechanisms underlying morphine tolerance are complex and still unclear. Recently, the activation...

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Detalles Bibliográficos
Autores principales: Di Cesare Mannelli, Lorenzo, Corti, Francesca, Micheli, Laura, Zanardelli, Matteo, Ghelardini, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385605/
https://www.ncbi.nlm.nih.gov/pubmed/25874232
http://dx.doi.org/10.1155/2015/894732