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Delay of Morphine Tolerance by Palmitoylethanolamide
In spite of the potency and efficacy of morphine, its clinical application for chronic persistent pain is limited by the development of tolerance to the antinociceptive effect. The cellular and molecular mechanisms underlying morphine tolerance are complex and still unclear. Recently, the activation...
Autores principales: | Di Cesare Mannelli, Lorenzo, Corti, Francesca, Micheli, Laura, Zanardelli, Matteo, Ghelardini, Carla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385605/ https://www.ncbi.nlm.nih.gov/pubmed/25874232 http://dx.doi.org/10.1155/2015/894732 |
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