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3-(3-Pyridylmethylidene)-2-indolinone Reduces the Severity of Colonic Injury in a Murine Model of Experimental Colitis

Nrf2 is the key transcription factor regulating the antioxidant response which is crucial for cytoprotection against extracellular stresses. Numerous in vivo studies indicate that Nrf2 plays a protective role in anti-inflammatory response. 3-(3-Pyridylmethylidene)-2-indolinone (PMID) is a synthesize...

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Detalles Bibliográficos
Autores principales: Wang, Kun-Ping, Zhang, Chao, Zhang, Shou-Guo, Liu, En-Dong, Dong, Lan, Kong, Xiang-Zhen, Cao, Peng, Hu, Chun-Ping, Zhao, Ke, Zhan, Yi-Qun, Dong, Xiao-Ming, Ge, Chang-Hui, Yu, Miao, Chen, Hui, Wang, Lin, Yang, Xiao-Ming, Li, Chang-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385690/
https://www.ncbi.nlm.nih.gov/pubmed/25874026
http://dx.doi.org/10.1155/2015/959253