Cas9 specifies functional viral targets during CRISPR-Cas adaptation

Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci and their associated (Cas) proteins provide adaptive immunity against viral infection in prokaryotes. Upon infection, short phage sequences known as spacers integrate between CRISPR repeats and are transcribed into small RNA gu...

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Detalles Bibliográficos
Autores principales: Heler, Robert, Samai, Poulami, Modell, Joshua W., Weiner, Catherine, Goldberg, Gregory W., Bikard, David, Marraffini, Luciano A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385744/
https://www.ncbi.nlm.nih.gov/pubmed/25707807
http://dx.doi.org/10.1038/nature14245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385744/
https://www.ncbi.nlm.nih.gov/pubmed/25707807
http://dx.doi.org/10.1038/nature14245

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