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Chloride channel-3 promotes tumor metastasis by regulating membrane ruffling and is associated with poor survival

The chloride channel-3 (ClC-3) protein is known to be a component of Cl(−) channels involved in cell volume regulation or acidification of intracellular vesicles. Here, we report that ClC-3 was highly expressed in the cytoplasm of metastatic carcinomatous cells and accelerated cell migration in vitr...

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Detalles Bibliográficos
Autores principales: Xu, Bin, Jin, Xiaobao, Min, Ling, Li, Qin, Deng, Lulu, Wu, Hui, Lin, Guixian, Chen, Lixin, Zhang, Haifeng, Li, Chunmei, Wang, Liwei, Zhu, Jiayong, Wang, Weizhang, Chu, Fujiang, Shen, Juan, Li, Hongzhi, Mao, Jianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385862/
https://www.ncbi.nlm.nih.gov/pubmed/25537517