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Genetic alterations of histone lysine methyltransferases and their significance in breast cancer

Histone lysine methyltransferases (HMTs), a large class of enzymes that catalyze site-specific methylation of lysine residues on histones and other proteins, play critical roles in controlling transcription, chromatin architecture, and cellular differentiation. However, the genomic landscape and cli...

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Detalles Bibliográficos
Autores principales: Liu, Lanxin, Kimball, Sarah, Liu, Hui, Holowatyj, Andreana, Yang, Zeng-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385864/
https://www.ncbi.nlm.nih.gov/pubmed/25537518