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Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model

Chronic liver inflammation is a crucial event in the development and growth of hepatocellular carcinoma (HCC). Compelling evidence has shown that interleukin-6 (IL-6)/gp130-dependent signaling has a fundamental role in liver carcinogenesis. Thus, in the present study we aimed to investigate the role...

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Detalles Bibliográficos
Autores principales: Hatting, M, Spannbauer, M, Peng, J, Al Masaoudi, M, Sellge, G, Nevzorova, Y A, Gassler, N, Liedtke, C, Cubero, F J, Trautwein, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385909/
https://www.ncbi.nlm.nih.gov/pubmed/25741592
http://dx.doi.org/10.1038/cddis.2014.590