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Lack of gp130 expression in hepatocytes attenuates tumor progression in the DEN model
Chronic liver inflammation is a crucial event in the development and growth of hepatocellular carcinoma (HCC). Compelling evidence has shown that interleukin-6 (IL-6)/gp130-dependent signaling has a fundamental role in liver carcinogenesis. Thus, in the present study we aimed to investigate the role...
Autores principales: | Hatting, M, Spannbauer, M, Peng, J, Al Masaoudi, M, Sellge, G, Nevzorova, Y A, Gassler, N, Liedtke, C, Cubero, F J, Trautwein, C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385909/ https://www.ncbi.nlm.nih.gov/pubmed/25741592 http://dx.doi.org/10.1038/cddis.2014.590 |
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