T-cell intracellular antigens function as tumor suppressor genes

Knockdown of T-cell intracellular antigens TIA1 and TIAR in transformed cells triggers cell proliferation and tumor growth. Using a tetracycline-inducible system, we report here that an increased expression of TIA1 or TIAR in 293 cells results in reduced rates of cell proliferation. Ectopic expressi...

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Detalles Bibliográficos
Autores principales: Sánchez-Jiménez, C, Ludeña, M D, Izquierdo, J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385921/
https://www.ncbi.nlm.nih.gov/pubmed/25741594
http://dx.doi.org/10.1038/cddis.2015.43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385921/
https://www.ncbi.nlm.nih.gov/pubmed/25741594
http://dx.doi.org/10.1038/cddis.2015.43

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