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Arundic acid attenuates retinal ganglion cell death by increasing glutamate/aspartate transporter expression in a model of normal tension glaucoma

Glaucoma is the second leading cause of blindness worldwide and is characterized by gradual visual impairment owing to progressive loss of retinal ganglion cells (RGCs) and their axons. Glutamate excitotoxicity has been implicated as a mechanism of RGC death in glaucoma. Consistent with this claim,...

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Detalles Bibliográficos
Autores principales: Yanagisawa, M, Aida, T, Takeda, T, Namekata, K, Harada, T, Shinagawa, R, Tanaka, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385923/
https://www.ncbi.nlm.nih.gov/pubmed/25789968
http://dx.doi.org/10.1038/cddis.2015.45