Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim

Subversion of host cell apoptosis is an important survival strategy for viruses to ensure their own proliferation and survival. Certain viruses express proteins homologous in sequence, structure and function to mammalian pro-survival B-cell lymphoma 2 (Bcl-2) proteins, which prevent rapid clearance...

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Detalles Bibliográficos
Autores principales: Marshall, B, Puthalakath, H, Caria, S, Chugh, S, Doerflinger, M, Colman, P M, Kvansakul, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385930/
https://www.ncbi.nlm.nih.gov/pubmed/25766319
http://dx.doi.org/10.1038/cddis.2015.52

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385930/
https://www.ncbi.nlm.nih.gov/pubmed/25766319
http://dx.doi.org/10.1038/cddis.2015.52

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