BAG3 regulates formation of the SNARE complex and insulin secretion

Insulin release in response to glucose stimulation requires exocytosis of insulin-containing granules. Glucose stimulation of beta cells leads to focal adhesion kinase (FAK) phosphorylation, which acts on the Rho family proteins (Rho, Rac and Cdc42) that direct F-actin remodeling. This process requi...

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Detalles Bibliográficos
Autores principales: Iorio, V, Festa, M, Rosati, A, Hahne, M, Tiberti, C, Capunzo, M, De Laurenzi, V, Turco, M C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385931/
https://www.ncbi.nlm.nih.gov/pubmed/25766323
http://dx.doi.org/10.1038/cddis.2015.53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385931/
https://www.ncbi.nlm.nih.gov/pubmed/25766323
http://dx.doi.org/10.1038/cddis.2015.53

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