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BAG3 regulates formation of the SNARE complex and insulin secretion

Insulin release in response to glucose stimulation requires exocytosis of insulin-containing granules. Glucose stimulation of beta cells leads to focal adhesion kinase (FAK) phosphorylation, which acts on the Rho family proteins (Rho, Rac and Cdc42) that direct F-actin remodeling. This process requi...

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Detalles Bibliográficos
Autores principales:	Iorio, V, Festa, M, Rosati, A, Hahne, M, Tiberti, C, Capunzo, M, De Laurenzi, V, Turco, M C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385931/ https://www.ncbi.nlm.nih.gov/pubmed/25766323 http://dx.doi.org/10.1038/cddis.2015.53

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