Homology and enzymatic requirements of microhomology-dependent alternative end joining

Nonhomologous DNA end joining (NHEJ) is one of the major double-strand break (DSB) repair pathways in higher eukaryotes. Recently, it has been shown that alternative NHEJ (A-NHEJ) occurs in the absence of classical NHEJ and is implicated in chromosomal translocations leading to cancer. In the presen...

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Detalles Bibliográficos
Autores principales: Sharma, S, Javadekar, S M, Pandey, M, Srivastava, M, Kumari, R, Raghavan, S C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385936/
https://www.ncbi.nlm.nih.gov/pubmed/25789972
http://dx.doi.org/10.1038/cddis.2015.58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385936/
https://www.ncbi.nlm.nih.gov/pubmed/25789972
http://dx.doi.org/10.1038/cddis.2015.58

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